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Kidney cancer patients have ‘more and more hope’ after promising Dana-Farber study

Published Wed, 05 Mar 2025 02:33:05 GMT

A promising new study out of Dana-Farber Cancer Institute showing that a three-drug combination slows the progression of advanced kidney cancer gives patients “more and more hope,” the lead researcher told the Herald on Wednesday.Kidney cancer patients treated with the three-drug combo — a targeted kinase inhibitor added to a two-drug immunotherapy combo — had a 27% lower risk of progression or death compared to those on the two immunotherapy drugs.“There had never been a study that showed the three drugs were superior to the two,” said Toni Choueiri, the director of the Lank Center for Genitourinary Cancer at Dana-Farber, and who’s the lead author of the COSMIC-313 study.“This gives kidney cancer patients more and more hope,” he later added.Rates of kidney cancer in the U.S. are on the rise, especially among men, and an estimated 82,000 Americans will be diagnosed with kidney cancer this year.The COSMIC-313 study looked at the c...

Ex-Heat Markieff Morris: Heat too ‘talented’ and ‘tough’ for Knicks

Published Wed, 05 Mar 2025 02:33:05 GMT

Before the Knicks tackled their 3-1 deficit and a must-win Game 5, Markieff Morris, an NBA veteran and a recent Heat player, predicted their quick downfall because the matchup was unfavorable.“When you talk about Miami, they’re more talented, more tough and battle tested,” Morris, who played last season with the Heat, said on his Youtube series “Run Your Race.” “The three things you need, bro. Miami gets to the point when you need one more guy. And they’re doing this without Tyler Herro. Imagine if they had Tyler. This would’ve probably been a sweep.”Herro, the Heat’s third leading scorer in the regular season, has missed the entire series because of a broken right hand. Still, the Heat emerged from the Play-In Tournament to pummel the top-seeded Bucks in the first round. Then they pushed the Knicks to the brink before Wednesday’s Game 5.“I got Heat, 4-1. I think they close it out in five,” said Morri...

David Pastrnak a finalist for Ted Lindsay Award

Published Wed, 05 Mar 2025 02:33:05 GMT

David Pastrnak is one of the three finalists for the Ted Lindsay Award, which is given out by the NHL Players Association to the league’s most outstanding player as voted on by the players.Pastrnak became the first Bruin to hit the 60-goal mark since Phil Esposito did it in 1974-75. With 61-52-113 totals, Pastrnak also broke the 100-point plateau for the first time in his career.The other finalists are San Jose Shark Erik Karlsson, who topped the 100-point mark as a defenseman, and Edmonton Oiler Connor McDavid, who has to be considered the favorite after posting 64-89-153 totals.

Thousands of illegal immigrants flood the border as Title 42 nears end

Published Wed, 05 Mar 2025 02:33:05 GMT

The floodgates will open at the border at 11:59 p.m. Thursday when Title 42 ends and asylum restrictions are lifted.There are already reports of more than 10,300 migrants being apprehended Tuesday after they illegally attempted to enter the country, Fox News reported.The Biden administration said it will admit at least 100,000 Latin Americans seeking to reunite with family members in the United States, the Associated Press is reporting.It’s unclear why the administration has said it intends to welcome as many as 100,000 people from Honduras, Guatemala, and El Salvador under the family reunification parole processes.Julia Gelatt of the Migration Policy Center said U.S. State Department data shows at least 284,000 Latin Americans have filed family sponsorship petitions. That includes 78,000 Salvadorans, and up to 57,000 Hondurans, 58,000 Guatemalans, and 56,000 Colombians.“Our plan will deliver results, but it will take time for those results to be fully realized,” Homeland Secu...

Huge number of asylum seekers at US-Mexico border as COVID-19 restrictions end, new rules begin

Published Wed, 05 Mar 2025 02:33:05 GMT

CIUDAD JUAREZ, Mexico (AP) — The Biden administration on Thursday will begin denying asylum to migrants who arrive at the U.S.-Mexico border without first applying online or seeking protection in a country they passed through. It marks a fundamental shift in immigration policy as the U.S. readies for the end of a key pandemic restriction.Asylum seekers have been showing up at the border in huge numbers in anticipation of this week’s end of the use of a restriction known as Title 42. That rule has allowed the government to quickly expel migrants to Mexico. U.S. officials warned of difficult days ahead as the program tied to the COVID-19 pandemic expires this week.The rule announced Wednesday is part of new measures meant to crack down on illegal border crossings while creating new legal pathways. Families who cross the border will face curfews and monitoring; the head of household will wear an ankle bracelet as their cases are heard within 30 days.But there’s also a plan to open 100 ...

Prosecutors reveal link between terror defendant in Virginia and Islamic State ’empress’ from Kansas

Published Wed, 05 Mar 2025 02:33:05 GMT

ALEXANDRIA, Va. (AP) — A northern Virginia man arrested on terrorism charges has a husband-wife relationship with another American who was dubbed by authorities as an “ empress of ISIS ” for her work to establish an all-female battalion of the Islamic State, prosecutors said Wednesday. Mohammed Chhipa, 33, of Springfield, Virginia, was arrested last week on charges that he provided support to a terrorist group. Prosecutors allege that he transferred nearly $200,000 in cryptocurrency, with some of that money traced back to the Islamic State, to support Chhipa’s stated goal of helping smuggle female ISIS members from detention camps. Other funds remain unaccounted for. At a detention hearing Wednesday, prosecutors also disclosed a relationship between Chhipa and Allison Fluke-Ekren, an American from Kansas who is serving a 20-year prison sentence. Fluke-Ekren pleaded guilty last year to organizing and leading the Khatiba Nusaybah, a battalion in which roughly 100 women and girls...

Evacuee numbers fall in Alberta wildfires as firefighters brace for hot weather

Published Wed, 05 Mar 2025 02:33:05 GMT

The number of Alberta wildfire evacuees dropped Wednesday, but thousands remain out of their homes as firefighters braced for hotter, drier conditions in the coming days.  Colin Blair, director of the Alberta Emergency Management Agency, said the number of people out of their homes had fallen to below 18,000 from about 24,000.“Alberta continues to be under a provincial state of emergency,” he said Wednesday. Wildfire danger also forced the evacuation of part of a First Nation southwest of Edmonton. Corrine Bell with the O’Chiese First Nation Emergency Management Response Team said 103 people have been forced to leave the northern area of the reserve. One home has been lost and several have smoke damage.“We’re taking advantage of the gap in weather to tend to hot spots,” said Bell, adding the community is hoping the wind won’t change directions.Six nearby First Nations have also offered their fire services to help.“We’ve had an am...

New Mexico constitution focus of legal fight over oil and gas drilling

Published Wed, 05 Mar 2025 02:33:05 GMT

ALBUQUERQUE, N.M. (AP) — New Mexico and its Democratic governor are being sued over alleged failures to meet constitutional provisions for protecting against oil and gas pollution, a challenge that comes as the nation’s No. 2 oil-producing state rides a wave of record revenue from drilling in one of the most prolific collection of oil fields in the world.A coalition of environmental groups filed a lawsuit Wednesday in state district court, marking the first time the state constitution’s pollution-control clause has been the basis of such a legal claim. The 1971 amendment mandates that New Mexico prevent the despoilment of air, water and other natural resources. The challenge comes as New Mexico rides a wave of record revenue from development in the Permian Basin, currently one of the world’s most productive oil-producing regions. Oil-related revenue collections have surged passed five-year averages to fund a considerable amount of the state’s budget, including education ...

Gun safety proposals take big step forward at Minnesota Legislature

Published Wed, 05 Mar 2025 02:33:05 GMT

ST. PAUL, Minn, (AP) — A pair of gun violence prevention measures long sought by Minnesota Democrats were added Wednesday to a broad public safety budget bill, significantly raising their chances of becoming law.By unanimous voice votes, an all-Democratic House-Senate conference committee approved expanded background checks for gun transfers and a separate proposal for a “red flag law.” It would allow authorities to obtain “extreme risk protection orders” to temporarily take guns away from people deemed to be an imminent threat to others or themselves.But the gun measures still have a ways to go before they can become law. The conference committee had other work to complete on the package before sending it back to the full House and Senate. Lawmakers will then have to vote on the entire must-pass funding bill, which could make the choice easier to swallow for a handful of rural Democratic senators who have been on the fence. Democratic Gov. Tim Walz has pledged to sign it.Mich...

Indiana sheriff’s deputy killed in dog attack that left her son, 8, wounded

Published Wed, 05 Mar 2025 02:33:05 GMT

INDIANAPOLIS (AP) — A sheriff’s deputy died after being attacked in her Indianapolis home by a dog that also bit and wounded her 8-year-old son, authorities said Wednesday.Tamieka White, 46, was pronounced dead at the scene Tuesday night shortly after Indianapolis police officers responded to her home on the city’s east side, officials said. She had been a deputy with the Marion County Sheriff’s Office since 2007.Her young son was also bitten in the dog attack, which was reported about 7:45 p.m., officials said. He is recovering from non-life-threatening injuries, The Indianapolis Star reported. Indianapolis police said the attacking dog charged at a responding officer, who fatally shot the animal.A spokesperson with the Indianapolis Metropolitan Police Department said the dog was not owned by White, and police have identified the owner. They declined to release further information about the owner.Indianapolis Animal Care Services said in a statement that workers impound...